Washington, Mar 2. -A possible vaccine based on a nasal spray could protect against Alzheimer's disease and vascular brain damage, scientists reported in the journal Neurobiology of Aging.
Researchers at the Department of Neurology at the University of Tel Aviv, Israel, created this promising vaccine candidate to combat both this kind of senile dementia and cerebrovascular disease.
As part of a drug previously tested against influenza, expect were able to induce an immune response against the protein beta amyloid, whose accumulation in the brain is the cause of Alzheimer's disease, in animal biological models.
The vaccine activates macrophages, ehich are immune system cells that devour pathogens.
When the vaccine activates a large number of these macrophages, it eliminates the accumulation of amyloid beta protein in the cerebral vascular system, the scientists said in the publication.
They hope the vaccine that is based on a nasal spray to be useful for fighting mental decline of people with Alzheimer's disease, and to be able to repare cerebrovascular damage. (Prensa Latina)